Anti-SUMO1 antibody

Description

Recognises SUMO protein from Arabidopsis in Western blots with a strong signal and low background noise

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Application Data

Catalogue number crb2005271
Antibody Anti-SUMO1 antibody
Antigen Peptide Protein
Aliases Small Ubiquitin-like Modifier 1
Cross-Reactivity Arabidopsis, Rice, wheat, tomato, barley
Host Species Rabbit
Antibody Type Polyclonal
Validation 1:2000 (WB)
Target Arabidopsis SUMO1
Specificity Protein
Storage The product should be stored at -20°C for short term storage and long term storage. Avoid repeated freeze/ thaw cycles.
Citations

Orosa et al. Nat Commun. 2018 Dec 5;9(1):5185. doi: 10.1038/s41467-018-07696-8. PMID: 30518761

References

Conti et al., (2008). Small ubiquitin-like modifier proteases OVERLY TOLERANT TO SALT1 and -2 regulate salt stress responses in Arabidopsis. Plant Cell. 20(10):2894. PMID: 18849491

SMALL UBIQUITIN-LIKE MODIFIER (SUMO) protein is a small protein which can be conjugated to target proteins, a process known as SUMOylation. SUMOylation is a key post translational modification in plants that is involved in a wide array of biological processes ranging from development to environmental sensing. SUMOylation acts in a similar way to ubiqutination in that SUMOlayed proteins are targeted for degredation in the proteasome.

SUMO conjugation to its protein target involves an enzyme cascade involving activation of the SUMO polypeptide by SUMO protease and ligation of the SUMO polypeptide to lysine residues in target proteins. The removal of SUMO occurs by deconjugating SUMO protease enzymes. Plants have two SUMO E3 ligases, AtHPY2 and AtSIZ1, encoded by the Arabidopsis genome. SUMOylation is reversible due to the presence of SUMO proteases that possess de-conjugation activity and are able to cleave SUMO from target proteins.

Anti-SUMO1 antibody

Cat No. Pack Size Price Qty

crb2005271d

20ug

$165.00

crb2005271f

100ug

$330.00