Anti-citrullinated α-Enolase antibody

Description

α-Enolase is a multifunctional enzyme; it is a neutrophin, a heat-shock protein, and a glycolytic catalyst. α-Enolase is also an autoantigen and stimulates immunoglobulin production. The production of antibodies against the citrullinated form of α-enolase (whereby positive Arg residues are converted into citrulline) is a hallmark of rheumatoid arthritis. α-Enolase also functions in the fibrolytic system, as a plasminogen receptor, and binds Myc to repress c-myc.

Application Data

Catalogue number crb2005010
Antibody Anti-citrullinated α-Enolase antibody
Antigen Peptide KLH conjugated synthetic peptide crb1200290e
Protein ID UniProtKB - P06733
Cross-Reactivity Human, rat, chicken
Host Species Rabbit
Antibody Type Polyclonal
Label Unconjugated
Concentration 1mg/ml
Validation WB/ELISA
Target citrullinated α-Enolase
Research Area Autoimmune
Family Enolase
Specificity Citrullinated form
Post-translational Modification Citrullination
Storage This material is supplied in PBS containing 0.01% sodium azide and 1% trehalose. The product should be stored at +4°C for short term storage and -20°C for long term storage. Avoid repeated freeze/ thaw cycles.
α-Enolase is a multifunctional enzyme; it is a neutrophin, a heat-shock protein, and a glycolytic catalyst. α-Enolase is also an autoantigen and stimulates immunoglobulin production. The production of antibodies against the citrullinated form of α-enolase (whereby positive Arg residues are converted into citrulline) is a hallmark of rheumatoid arthritis. α-Enolase also functions in the fibrolytic system, as a plasminogen receptor, and binds Myc to repress c-myc.

Anti-citrullinated α-Enolase antibody

Cat No. Pack Size Price Qty

crb2005010d

20ug

$150.00

crb2005010e

100ug

$300.00