Anti-Phospho-GluR2 (pS880) antibody

Description

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and is involved in synaptic transmission. Binding of L-glutamate to the receptor induces a conformation change which leads to Ion channel opening before rapidly desensitising.
Catalogue number crb2005005
Antibody Anti-Phospho-GluR2 (pS880) antibody
Antigen Peptide KLH conjugated synthetic peptide crb1200275e
Protein ID UniProtKB - Q14416
Aliases GRIA2, GLUR2, GLURB, GluA2, GluR-K2, HBGR2, glutamate ionotropic receptor AMPA type subunit 2
Cross-Reactivity Rat
Host Species Rabbit
Antibody Type Polyclonal
Label Unconjugated
Concentration 1mg/ml
Validation 1:1000 (WB), 1:1000 (ELISA)
Target phosphorylated GluR2 (pS880)
Research Area Neurodegenerative diseases
Family Glutamate-gated ion channel family
Post-translational Modification Phosphorylation of Serine 880
Storage This material is supplied in PBS containing 0.01% sodium azide and 1% trehalose. The product should be stored at +4°C for short term storage and -20°C for long term storage. Avoid repeated freeze/ thaw cycles.
References Liu et al., (2010). Journal of Alzheimer’s Disease. 21 (2): 655-66. Lin et al. (2007). J Neurosci. 27(50):13903-8. Huganir, et al. (2001).Neuropharmacology. 41:
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and is involved in synaptic transmission. Binding of L-glutamate to the receptor induces a conformation change which leads to Ion channel opening before rapidly desensitising.

Anti-Phospho-GluR2 (pS880) antibody

Cat No. Pack Size Price Qty

crb2005005d

20ug

$150.00

crb2005005e

50ug

$300.00

crb2115005e

Alexa Fluor® 488

$375.00