GluR1 peptide

Description

Antigenic peptide from the GluR1 subunit of AMPAR

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Catalogue number crb1200335
Antigen Peptide GluR1 peptide
Protein ID UniProtKB - P19490, P35438
Cross-Reactivity Human, Rat, Mouse
Storage -20°c
References

Khatib, T., Whiting, A., Chisholm, D., Redfern, C., Müller, B. and McCaffery, P. (2019). A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor. Mol Neurobiol. PMID: 30972628

 

Spaethling, J., Le, L. and Meaney, D. (2012). NMDA receptor mediated phosphorylation of GluR1 subunits contributes to the appearance of calcium-permeable AMPA receptors after mechanical stretch injury. Neurobiol Dis, 46(3), 646-654. PMID: 22426393

Specificity Protein

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) is an ionotropic transmembrane receptor for glutamate found throughout the central nervous system (CNS). AMPARs are composed of four types of subunits: GluR1/GluA1, GluR2/GluA2, GluR3/GluA3, and GluA4 (GluRA-D2), which combine to form heterotetramers. The function of AMPARs is determined by the composition of AMPAR subunits and GluR1 is found in the dorsal horn region of the spinal cord. GluR1-containing AMPARs are permeable to Ca2+ and the presence of GluR1-containing AMPARs in synapses contributes to the formation of long-term potential. GluR1 is involved in synaptic plasticity and the expression of the GluR1 gene is reduced with age.

GluR1 peptide

Cat No. Pack Size Price Qty

crb1200335e

50ug

$112.50