NR2A peptide

Description

Peptide corresponding to a region of the NR2A subunit of NMDA receptor

See full description

Catalogue number crb1200363
Antigen Peptide NR2A peptide
Protein ID UniProtKB - P35436
Aliases GRIN2A, GluN2A, NMDAR2A, NR2A, EIEE27, glutamate ionotropic receptor NMDA type subunit 2A/ NMDA NR2A Subunit
Cross-Reactivity Mouse, rat
Storage -20°C
References

Dong, L., Chen, J., Li, F., Gao, F., Wu, J., Miao, Y. and Wang, Z. (2013). Enhanced Expression of NR2B Subunits of NMDA Receptors in the Inherited Glaucomatous DBA/2J Mouse Retina. Neural Plast, 2013, 1-7. PMID: 24175101

 

Li, B., Sun, M., Zhang, L., Takahashi, S., Ma, W., Vinade, L., Kulkarni, A., Brady, R. and Pant, H. (2001). Regulation of NMDA receptors by cyclin-dependent kinase-5. PNAS, 98(22), 12742-12747. PMID: 11675505

Specificity Protein
N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ionotropic glutamate receptors that mediate excitatory synaptic transmission and play important roles in many aspects of nervous system function including: synaptic plasticity; learning and memory; neuronal development and circuit formation. In addition NMDARs have also been implicated in various neuronal disorders. NMDARs are heteromers consisting of an obligate NR1 subunit and most commonly one or two kinds of NR2 subunits or occasionally NR3 subunits.

The involvement of NMDAR in the central nervous system (CNS) has become a focus area for neurodegenerative diseases such as Alzheimer's disease, epilepsy and ischemic neuronal cell death.

NR2A peptide

Cat No. Pack Size Price Qty

crb1200363e

50ug

$112.50